Through the comments of a professional who works with people afflicted with HIV/AIDS, as well as a woman who is HIV-positive, this video focuses on the place of spirituality in HIV/AIDS. How a diagnosis impacts the whole person is described, including the spiritual dimension of the person. Explores how HIV/AIDS impacts the spiritual need for meaning and purpose, for forgiveness, and for love and relatedness. The impact of spiritual beliefs and practices in the management of HIV/AIDS is discussed, as well as how spirituality and religion are resources for those dealing with HIV/AIDS. Implications for clinicians are described.