This program examines the physical problems caused by the heavy and long-term use of psychoactive drugs, especially tobacco, alcohol, methamphetamines, and marijuana. Using animation, graphic medical footage, and interviews with experts in the field as well as those suffering from these diseases, this video explores the medical dangers of the method of use, the lifestyles of the users, and the drugs themselves. For example, injection drug use can cause abscesses, flesh-eating disease, hepatitis C, and AIDS; inhaling tobacco, marijuana, or crack can cause chronic bronchitis, emphysema, and lung cancer; ingesting excess alcohol can cause ulcers, cirrhosis of the liver, and brain damage; methamphetamines can damage blood vessels and heart muscles directly; tobacco can damage the lungs' alveoli and cause blood clots.
Also looks at the ramifications of the statement, "Continued use despite adverse consequences." Users talk about how their desire to continue smoking, injecting, inhaling, swallowing, or snorting drugs usually overcame any trepidation about potential medical consequences.